Manual C-X Bond Formation

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Cross-coupling reactions involving C-H and C-X bond functionalisation are commonplace in natural product synthesis and natural products, therapeutic agents, biological probes, and advanced materials. Much attention has been given to understanding the mechanistic strategies used to achieve this, making this a hot topic in recent years. In this edited book, contributions from across the globe examine these strategies, with a particular focus on palladium and copper, as well as iron — an emerging element in this field.


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Reviewing the recent literature, the book presents an in-depth understanding of the field, guiding the reader to achieving the best synthetic strategies for aromatic functionalisation. Organic and Organometallic chemists, as well as natural product and pharmaceutical scientists, will find this an essential guide to a major transformation currently underway in synthetic chemistry.

Chemistry of Cu III.

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C-C/C-X Bond Formation

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C-H Bond Activation Reaction [C-X Bond Formation] | TCI Deutschland GmbH

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    Nature of C-X bonds

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    Haloalkanes and Haloarenes - Nature of C-X bond

    Some features of this site may not work without it. Attention submitters: Web accessibility policy to take effect October 15, For more information, please see our web accessibility policy and web accessibility help for submitters. One way around this is to use redox noninnocent ligands that have the capacity to store electrons and then release them over the course of the catalytic cycle to limit the oxidation state changes that occur at the metal center.